Introduction
In our ongoing search for effective weight loss solutions, it’s important to understand how medications can help. One such medication that has caught people’s attention is Contrave, a prescription drug approved for weight loss. With so many options available, knowing how Contrave works and if it’s right for you can make a big difference.
In previous blogs, we have discussed various weight loss medications available in Canada, such as semaglutide, liraglutide, tizinapidine, and orlistat. This week, we are focusing on Contrave. In this blog, we will explore how Contrave can be part of a complete weight management plan, how it works, and who it might be suitable for. Whether you’re just starting your weight loss journey or looking for new strategies, understanding the role of medications like Contrave can be pivotal in achieving your goals.
What is Contrave?
Contrave combines two medications, naltrexone and bupropion, that work together to reduce hunger and control cravings. It is prescribed for weight loss in individuals who are either obese or overweight with weight-related health conditions such as diabetes, hypertension, or high cholesterol.
How Does Contrave Work?
As mentioned Contrave is a combination of two medications
Bupropion:
-Bupropion is primarily used as an antidepressant and smoking cessation aid. It affects the brain’s neurotransmitters, particularly norepinephrine and dopamine.
-By influencing these neurotransmitters, bupropion helps reduce appetite and cravings. It boosts the levels of these chemicals in the brain, which can lead to decreased hunger and a feeling of fullness.
Naltrexone
-Naltrexone is commonly used to treat alcohol and opioid dependence. It works by blocking opioid receptors in the brain.
-In the context of weight loss, naltrexone helps control cravings by affecting the brain’s reward system. This makes it easier to resist the temptation to overeat, particularly when it comes to high-calorie, unhealthy foods.
How does Contrave reduce eating behaviour?
Contrave reduces eating behavior through the combined effects of bupropion and naltrexone, which work together to target hunger and cravings. This dual approach can be more effective for weight loss compared to using either medication alone.
By balancing the chemicals in the brain that affect mood, appetite, and reward, Contrave helps regulate eating behavior. This balance makes it easier to stick to a healthy eating plan and achieve weight loss goals.
Who is a Good Candidate for Contrave Treatment?
Contrave is suitable for adults who:
– Have a body mass index (BMI) of 30 kg/m² or higher (obese).
– Have a BMI of 27 kg/m² or higher and suffer from a weight-related health condition.
– Are committed to a comprehensive weight management plan including diet, exercise and behaviour modification.
Who is not a Good Candidate for Contrave Treatment?
Contrave may not be suitable for:
Certainly! Here’s the information presented in a list format:
– Individuals with a history of seizures.
– Those currently using other forms of bupropion or any narcotic or opioid medications.
– Individuals who are pregnant or breastfeeding.
– Individuals less than 18 years of age.
How is Contrave Taken?
– Start with 1 tablet at night for 7 days.
– Then, take 1 tablet in the morning and 1 in the evening for 7 days.
– Increase to 2 tablets in the morning for the next 7 days.
– Finally, advance to 2 tablets in the morning and 2 in the evening.
– It typically takes about 4 weeks to reach the maximum dosage of 4 tablets per day, taken in divided doses.
– Always follow medical supervision during this dosage adjustment period.
12 Most FAQs about Contrave:
1. What are the common side effects of Contrave?
Common side effects of Contrave include nausea, constipation, insomnia, headaches, dry mouth, dizziness, increased heart rate, fatigue, digestive issues, and changes in taste. It’s important to discuss any side effects experienced with a healthcare provider for appropriate guidance and management.
2. How can these side effects be managed?
To manage the side effects of Contrave, consider these strategies:
– To avoid insomnia, it’s recommended to start taking the medication in the morning. Typically, this helps mitigate side effects, including insomnia, as the body adjusts to the medication.
– Combat nausea by staying hydrated, consuming dietary fibre, and having a light, fatty meal before taking Contrave.
– For mild headaches, rest, hydration, and over-the-counter pain relievers can provide relief.
– To manage constipation, incorporate fibre-rich foods into your diet and stay hydrated. Additionally, consider using fibre laxatives as recommended by your healthcare provider.
– Always discuss any concerns or new treatments with your healthcare provider for personalized guidance.
3. What are the serious side effects of Contrave?
Serious side effects of Contrave may include increased blood pressure and heart rate, seizures, liver damage, and mood changes like worsening depression or suicidal thoughts. It’s essential to promptly contact your healthcare provider if you experience any of these symptoms for evaluation and management.
4. Are Contrave and Wellbutrin the same?
No, Contrave and Wellbutrin are not the same. While both medications contain bupropion, which is also found in Wellbutrin, Contrave differs in that it contains another drug called naltrexone specifically formulated for weight loss purposes.
5. How much weight can you expect to lose with Contrave?
Patients can typically expect to lose approximately 5-10% of their body weight over the course of a year when using Contrave in conjunction with diet and exercise. This information is based on clinical studies and prescribing information provided by the manufacturer.
6. What is the recommended age for using Contrave?
Contrave is recommended for adults aged 18 and older.
7. Can I use pain medications with Contrave?
When using Contrave, it’s generally safe to take common pain medications like ibuprofen, naproxen, or acetaminophen.
However, caution is advised when considering narcotics such as oxycodone (percoets) morphine, codeine, or tramadol. This caution arises from Contrave’s inclusion of naltrexone, which can interfere with the effectiveness of these narcotics and increase the risk of withdrawal symptoms.
8. Can I take Contrave if I am taking other antidepressants?
Yes, in most cases, it’s safe to take Contrave alongside other antidepressants. However, it’s crucial to discuss this with your physician to ensure there are no potential interactions or adverse effects. Mistakes can occur when patients forget that Contrave contains antidepressant and anti-anxiety medications, leading to potential complications if not communicated to their psychiatrist or healthcare provider. Always keep your healthcare team informed about all medications you are taking to ensure safe and effective treatment.
9. I have had bariatric surgery; can I safely use Contrave?
Post-bariatric surgery patients can safely use Contrave; bariatric surgery is not a contraindication for Contrave use.
10. Will Contrave help me quit smoking?
Yes, Contrave can help individuals quit smoking. It’s especially beneficial for those who are obese, experiencing mood issues, and are smokers. Contrave should be considered as a first-line option in such cases.
11. What should I eat when I’m on Contrave?
When taking Contrave, there are no specific food requirements. It’s important to maintain a balanced diet with plenty of fruits, vegetables, lean proteins, and whole grains. Avoid strict food restrictions and focus on moderation in your eating habits. Remember to stay hydrated and listen to your body’s hunger and fullness cues
12. If I stop taking Contrave, will I regain back the weight?
If you stop taking Contrave, there’s a possibility of regaining weight, especially if healthy eating and exercise habits aren’t maintained. It’s essential to have a plan for sustainable weight management, which may involve adopting healthy lifestyle habits to help maintain weight loss over the long term.
Conclusion – How Modest Medix Can Help
At Modest Medix, a weight management center in Mississauga, Ontario, our Medical Doctor-supervised weight management program takes a holistic and comprehensive approach to weight loss and health improvement. Our multidisciplinary team, including registered dietitians (RD), social workers (SW), nurses, and health educators, collaborates to provide personalized care tailored to each individual’s needs. We believe in a sustainable, realistic, reliable, and enjoyable approach to weight management through one-on-one counseling catered to your needs.
Contrave is one of the tools we use to help manage weight effectively, but it’s just a part of our broader strategy that includes emotional regulation, health education, and a supportive community. Contrave not only aids in weight management but also assists with mood regulation and emotional stability. Let us help you achieve your health goals in a sustainable and supportive environment.
